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色谱-质谱联用技术测定人体内类固醇激素的研究进展

钱跹,  赵亮,  吕磊,  张海,  李悦悦,  张国庆

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钱跹, 赵亮, 吕磊, 张海, 李悦悦, 张国庆. 色谱-质谱联用技术测定人体内类固醇激素的研究进展[J]. 药学实践与服务, 2014, 32(3): 176-180,190. doi: 10.3969/j.issn.1006-0111.2014.03.004
引用本文: 钱跹, 赵亮, 吕磊, 张海, 李悦悦, 张国庆. 色谱-质谱联用技术测定人体内类固醇激素的研究进展[J]. 药学实践与服务, 2014, 32(3): 176-180,190. doi: 10.3969/j.issn.1006-0111.2014.03.004
shu
QIAN Xian, ZHAO Liang, LU Lei, ZHANG Hai, LI Yueyue, ZHANG Guoqing. Research progress in steroid hormone analysis in vivo by chromatography-mass spectrometry[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(3): 176-180,190. doi: 10.3969/j.issn.1006-0111.2014.03.004
Citation: QIAN Xian, ZHAO Liang, LU Lei, ZHANG Hai, LI Yueyue, ZHANG Guoqing. Research progress in steroid hormone analysis in vivo by chromatography-mass spectrometry[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(3): 176-180,190. doi: 10.3969/j.issn.1006-0111.2014.03.004
shu

色谱-质谱联用技术测定人体内类固醇激素的研究进展

doi: 10.3969/j.issn.1006-0111.2014.03.004

  • 第二军医大学东方肝胆外科医院药材科, 上海 200438

Research progress in steroid hormone analysis in vivo by chromatography-mass spectrometry

  • Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China

  • 摘要: 类固醇激素是高效能的生物化学物质,在多种生理活动中发挥显著的调节作用,但在体内的含量极低,因此对其进行准确定量具有重要意义。在各种检测方法中,色谱-质谱联用技术因具有高效、快速、灵敏的优点而得以广泛应用。笔者综述近年来色谱-质谱联用技术在内源性类固醇激素测定中的应用,为进一步的临床研究提供参考依据。
    Abstract: Steroid hormones were chemical compounds of high efficiency, which played a significant role in various physiological activities. However, the concentrations of hormones in vivo were extremely low, so it was very important for their accurate quantification. Chromatography-mass spectrometry technology was widely employed because of advances in high efficient, rapid and sensitive. The application of steroid hormone analysis by chromatography-mass spectrometry was reviewed in this paper, which could provide reference for furthuer clinical research.
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  • 收稿日期:  2013-08-28
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色谱-质谱联用技术测定人体内类固醇激素的研究进展

doi: 10.3969/j.issn.1006-0111.2014.03.004
  • 第二军医大学东方肝胆外科医院药材科, 上海 200438
  • 收稿日期: 2013-08-28
  • 修回日期: 2014-01-14

摘要: 类固醇激素是高效能的生物化学物质,在多种生理活动中发挥显著的调节作用,但在体内的含量极低,因此对其进行准确定量具有重要意义。在各种检测方法中,色谱-质谱联用技术因具有高效、快速、灵敏的优点而得以广泛应用。笔者综述近年来色谱-质谱联用技术在内源性类固醇激素测定中的应用,为进一步的临床研究提供参考依据。

English Abstract

钱跹, 赵亮, 吕磊, 张海, 李悦悦, 张国庆. 色谱-质谱联用技术测定人体内类固醇激素的研究进展[J]. 药学实践与服务, 2014, 32(3): 176-180,190. doi: 10.3969/j.issn.1006-0111.2014.03.004
引用本文: 钱跹, 赵亮, 吕磊, 张海, 李悦悦, 张国庆. 色谱-质谱联用技术测定人体内类固醇激素的研究进展[J]. 药学实践与服务, 2014, 32(3): 176-180,190. doi: 10.3969/j.issn.1006-0111.2014.03.004
shu
QIAN Xian, ZHAO Liang, LU Lei, ZHANG Hai, LI Yueyue, ZHANG Guoqing. Research progress in steroid hormone analysis in vivo by chromatography-mass spectrometry[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(3): 176-180,190. doi: 10.3969/j.issn.1006-0111.2014.03.004
Citation: QIAN Xian, ZHAO Liang, LU Lei, ZHANG Hai, LI Yueyue, ZHANG Guoqing. Research progress in steroid hormone analysis in vivo by chromatography-mass spectrometry[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(3): 176-180,190. doi: 10.3969/j.issn.1006-0111.2014.03.004
shu

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