2023 Vol. 41, No. 8
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2023, 41(8): 455-458, 477.
doi: 10.12206/j.issn.2097-2024.202105132
Abstract:
Sodium dichloroacetate (DCA) is a small molecule drug usually administered orally. It has therapeutic effects against several diseases, such as metabolic syndrome, cardiovascular and cerebrovascular diseases, and several solid tumors. In this review,...
Sodium dichloroacetate (DCA) is a small molecule drug usually administered orally. It has therapeutic effects against several diseases, such as metabolic syndrome, cardiovascular and cerebrovascular diseases, and several solid tumors. In this review,...
2023, 41(8): 459-464, 471.
doi: 10.12206/j.issn.2097-2024.202204059
Abstract:
As a complex and large microbial community colonized in the human body, the intestinal flora and its metabolites short-chain fatty acids (SCFAs) play an important role in participating in human metabolism, resisting pathogens, and regulating immune m...
As a complex and large microbial community colonized in the human body, the intestinal flora and its metabolites short-chain fatty acids (SCFAs) play an important role in participating in human metabolism, resisting pathogens, and regulating immune m...
2023, 41(8): 465-471.
doi: 10.12206/j.issn.2097-2024.202204031
Abstract:
Bavachinin is a dihydroflavone isolated from dried ripe fruits of Psoralea corylifolia L., which has various pharmacological activities, such as anti-tumor, anti-virus, anti-diabetes, anti-inflammatory and neuroprotective, and good potential in clini...
Bavachinin is a dihydroflavone isolated from dried ripe fruits of Psoralea corylifolia L., which has various pharmacological activities, such as anti-tumor, anti-virus, anti-diabetes, anti-inflammatory and neuroprotective, and good potential in clini...
2023, 41(8): 472-477.
doi: 10.12206/j.issn.2097-2024.202301008
Abstract:
Hippo signal pathway is one of the main signal pathways regulating cell proliferation and apoptosis in multicellular animals, which plays a vital role in the maintenance of tissue homeostasis and the regulation of organ growth. Most mammals have limi...
Hippo signal pathway is one of the main signal pathways regulating cell proliferation and apoptosis in multicellular animals, which plays a vital role in the maintenance of tissue homeostasis and the regulation of organ growth. Most mammals have limi...
2023, 41(8): 478-484.
doi: 10.12206/j.issn.2097-2024.202212056
Abstract:
Objective To investigate the effect and mechanism of astragaloside Ⅳ(AS-Ⅳ) activating ROCK/JNK to regulate autophagy in improving isoproterenol (ISO) induced myocardial fibrosis (MF) in mice. Methods T he mice were randomly divided into control op...
2023, 41(8): 485-491.
doi: 10.12206/j.issn.2097-2024.202208040
Abstract:
Objective To explore the possible mechanism of Radix Paeoniae Alba on hepatic fibrosis based on network pharmacology. Methods T cmsp database was used to screen the active components of Paeonia alba. With the help of PubChem and Swiss target predi...
2023, 41(8): 492-495, 508.
doi: 10.12206/j.issn.2097-2024.202109095
Abstract:
Objective To optimize the supercritical CO2 extraction conditions of volatile oil from Wenjing Huoxue cataplasm. Methods On the basis of single factor investigation on the comprehensive score of extraction yield , osthole content and isoimp...
2023, 41(8): 496-500.
doi: 10.12206/j.issn.2097-2024.202202001
Abstract:
Objective To establish a quality control method for Lvxintong Rugao. Methods K etoconazole, Halcinonide and Neomycin sulfate were identified by TLC. The content of Ketoconazole and Halcinonide were determined by HPLC. The chromatographic column of...
2023, 41(8): 501-508.
doi: 10.12206/j.issn.2097-2024.202109069
Abstract:
Objective To prepare a sustained-release membrane with longer adhesion time and dissolution time, and compare it with the commercially available oral ulcer membrane. Method Adhesion strength, adhesion time, swelling coefficient, dissolution t...
2023, 41(8): 509-514, 518.
doi: 10.12206/j.issn.2097-2024.202301026
Abstract:
Objective To analyze the research status and predict the development trend of clinical comprehensive evaluation of drugs in China, and to provide reference for clinical comprehensive evaluation. Methods C NKI, Wanfang and VIP database were used to...
2023, 41(8): 515-518.
doi: 10.12206/j.issn.2097-2024.202207080
Abstract:
Objective To investigate the clinical efficacy of Kangfuxin solution combined with lidocaine and gentamicin in the treatment of oral ulcers. Method A total of 120 patients with oral ulcer admitted to Tongzhou District Maternity and Child Health C...
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