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2023 Vol. 41, No. 8

Cover Catalogue
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Medical research progresses on sodium dichloroacetate
LU Cheng, JIANG Yu, PENG Cheng, YANG Lijun, XIE Hehui
2023, 41(8): 455-458, 477. doi: 10.12206/j.issn.2097-2024.202105132
Abstract(5909) HTML (1707) PDF (1227KB)(80)
Abstract:
Sodium dichloroacetate (DCA) is a small molecule drug usually administered orally. It has therapeutic effects against several diseases, such as metabolic syndrome, cardiovascular and cerebrovascular diseases, and several solid tumors. In this review,...
Review of bone metabolism regulated by intestinal flora and the application of Traditional Chinese Medicine
FAN Weiqing, XIA Tianshuang, JIANG Yiping, NIAN Hua, XIN Hailiang
2023, 41(8): 459-464, 471. doi: 10.12206/j.issn.2097-2024.202204059
Abstract(7066) HTML (4845) PDF (1357KB)(41)
Abstract:
As a complex and large microbial community colonized in the human body, the intestinal flora and its metabolites short-chain fatty acids (SCFAs) play an important role in participating in human metabolism, resisting pathogens, and regulating immune m...
Progress on pharmacological activities and hepatotoxicity of bavachinin
ZHOU Rongrui, WEI Yanping, CHEN Wei, DING Qianqian, WANG Jinxin, ZU Xianpeng
2023, 41(8): 465-471. doi: 10.12206/j.issn.2097-2024.202204031
Abstract(7489) HTML (1679) PDF (1037KB)(36)
Abstract:
Bavachinin is a dihydroflavone isolated from dried ripe fruits of Psoralea corylifolia L., which has various pharmacological activities, such as anti-tumor, anti-virus, anti-diabetes, anti-inflammatory and neuroprotective, and good potential in clini...
Research progress on the mechanism of Hippo signaling pathway in organ regeneration
CHEN Shuai, LI Anpeng, LI Xingxing, ZHAO Qingjie, ZOU Yan
2023, 41(8): 472-477. doi: 10.12206/j.issn.2097-2024.202301008
Abstract(8048) HTML (2450) PDF (1440KB)(43)
Abstract:
Hippo signal pathway is one of the main signal pathways regulating cell proliferation and apoptosis in multicellular animals, which plays a vital role in the maintenance of tissue homeostasis and the regulation of organ growth. Most mammals have limi...
Alleviation of isoproterenol-induced myocardial fibrosis in mice by autophagy regulated by Astragaloside through activating ROCK/JNK pathway
WU Feifei, ZHANG Xiaoqi, LIAN Jing, YANG Jing, ZHAI Mengen, QIAO Rui, XU Chennian, YANG Tingting
2023, 41(8): 478-484. doi: 10.12206/j.issn.2097-2024.202212056
Abstract(3473) HTML (1424) PDF (3105KB)(18)
Abstract:
Objective  To investigate the effect and mechanism of astragaloside Ⅳ(AS-Ⅳ) activating ROCK/JNK to regulate autophagy in improving isoproterenol (ISO) induced myocardial fibrosis (MF) in mice.   Methods  The mice were randomly divided into control op...
Mechanism of Radix Paeoniae Alba in the treatment of liver fibrosis based on network pharmacology
HUANG Qing, SHI Chunyan
2023, 41(8): 485-491. doi: 10.12206/j.issn.2097-2024.202208040
Abstract(6195) HTML (2589) PDF (2448KB)(106)
Abstract:
Objective  To explore the possible mechanism of Radix Paeoniae Alba on hepatic fibrosis based on network pharmacology.   Methods  Tcmsp database was used to screen the active components of Paeonia alba. With the help of PubChem and Swiss target predi...
Extraction Technology of Volatile Oil from Wenjing Huoxue Cataplasm
PENG Huili, ZHAO Lina, CHENG Yanqin, ZHAO Liyan, FENG Yinglu, LI Mingchun
2023, 41(8): 492-495, 508. doi: 10.12206/j.issn.2097-2024.202109095
Abstract(2290) HTML (1013) PDF (1509KB)(9)
Abstract:
Objective   To optimize the supercritical CO2 extraction conditions of volatile oil from Wenjing Huoxue cataplasm.   Methods   On the basis of single factor investigation on the comprehensive score of extraction yield , osthole content and isoimp...
Study on the Quality Control Standard of Lvxintong Rugao
LIU Binguo, WANG Xiaoli, YE Shengying
2023, 41(8): 496-500. doi: 10.12206/j.issn.2097-2024.202202001
Abstract(2817) HTML (1448) PDF (1085KB)(6)
Abstract:
Objective  To establish a quality control method for Lvxintong Rugao.   Methods  Ketoconazole, Halcinonide and Neomycin sulfate were identified by TLC. The content of Ketoconazole and Halcinonide were determined by HPLC. The chromatographic column of...
Study on preparation technology of long-acting sustained-release oral ulcer membrane based on analytic hierarchy process and orthogonal design
XU Xiang, CHEN Xu, KE Yuejiao, LIU Zhihong, CHEN Yufang, ZHOU Xin, SONG Hongtao
2023, 41(8): 501-508. doi: 10.12206/j.issn.2097-2024.202109069
Abstract(3509) HTML (1641) PDF (1526KB)(14)
Abstract:
Objective  To prepare a sustained-release membrane with longer adhesion time and dissolution time, and compare it with the commercially available oral ulcer membrane.   Method   Adhesion strength, adhesion time, swelling coefficient, dissolution t...
Visual analysis of clinical comprehensive evaluation of drugs in China by bibliometric analysis
LI Juan, PANG Tao, XU Deduo, MA Erli, CHEN Weidong, ZHANG Feng, LIU Binglong
2023, 41(8): 509-514, 518. doi: 10.12206/j.issn.2097-2024.202301026
Abstract(4440) HTML (1809) PDF (1968KB)(21)
Abstract:
Objective  To analyze the research status and predict the development trend of clinical comprehensive evaluation of drugs in China, and to provide reference for clinical comprehensive evaluation.   Methods  CNKI, Wanfang and VIP database were used to...
Clinical effect of Kangfuxin solution combined with lidocaine and gentamicin in the treatment of oral ulcer
ZHAO Ling, WU Yanan, XU Mingyuan
2023, 41(8): 515-518. doi: 10.12206/j.issn.2097-2024.202207080
Abstract(4817) HTML (1679) PDF (933KB)(11)
Abstract:
Objective  To investigate the clinical efficacy of Kangfuxin solution combined with lidocaine and gentamicin in the treatment of oral ulcers.   Method  A total of 120 patients with oral ulcer admitted to Tongzhou District Maternity and Child Health C...