更昔洛韦葡萄糖注射液的溶血性、过敏性及血管刺激性考察
Study of hemolysis, stimulation and hypersensitivity on blood vessel of ganciclovir glucose injection
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摘要: 目的: 考察更昔洛韦葡萄糖注射液的溶血性、过敏性和对静脉血管的刺激作用。 方法: 以豚鼠及新西兰兔为实验动物,给予本注射液后观察动物有无红肿、充血、出血和坏死等刺激作用及溶血和过敏现象。 结果: 滴注部位未出现明显的红肿、充血、坏死等刺激反应及过敏现象;对家兔红细胞未产生溶血和凝集作用。 结论: 更昔洛韦葡萄糖注射液无血管刺激性、过敏性及溶血性。Abstract: Objective: To observe the hemolysis, stimulation and hypersensitivity of ganciclovir glucose injection. Methods: The stimulation reaction on blood vessel of rabbit,the hemolysis and agglomeration reaction on vitro-body red cell of rabbit and the hypersensitivity reaction on guine-pig of ganciclovir glucose injection were studied. Results: The results showed no stimulation on blood vessel of rabbits, no hemolysis and agglomeration on vitro-body red cells of rabbit and no hypersensitive action on guinea-pig. Conclusion: Ganciclovir glucose injection has no hemolysis,hypersensitive and stimulative reaction.
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Key words:
- hemolysis /
- stimulation /
- ganciclovir /
- injection
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