2012 Vol. 30, No. 6
Display Method:
2012, 30(6): 401-404,446.
doi: 10.3969/j.issn.1006-0111.2012.06.001
Abstract:
Counterfeit drugs not only affected drug safe and function, but also disturbed the commerce and social order. It had become so urgently to combat counterfeit drugs. Recently, Raman spectroscopy had been a more and more popular technique in the fast d...
Counterfeit drugs not only affected drug safe and function, but also disturbed the commerce and social order. It had become so urgently to combat counterfeit drugs. Recently, Raman spectroscopy had been a more and more popular technique in the fast d...
2012, 30(6): 405-407,453.
doi: 10.3969/j.issn.1006-0111.2012.06.002
Abstract:
Sugammadex had been licensed for reversal of rocuronium and vecuronium induced neuromuscular blockade in Europe since 2008, which had shown to be efficacious and had a good safety profile so far. The potential for Sugammadex to change the management ...
Sugammadex had been licensed for reversal of rocuronium and vecuronium induced neuromuscular blockade in Europe since 2008, which had shown to be efficacious and had a good safety profile so far. The potential for Sugammadex to change the management ...
2012, 30(6): 408-411.
doi: 10.3969/j.issn.1006-0111.2012.06.003
Abstract:
Chronic obstructive pulmonary disease(COPD), the fourth leading cause of death in the world, represented an important public health challenge. Appropriate medicine therapy in COPD was used to reduce symptoms, the frequency and severity of exacerbatio...
Chronic obstructive pulmonary disease(COPD), the fourth leading cause of death in the world, represented an important public health challenge. Appropriate medicine therapy in COPD was used to reduce symptoms, the frequency and severity of exacerbatio...
2012, 30(6): 412-414,436.
doi: 10.3969/j.issn.1006-0111.2012.06.004
Abstract:
The research progress on the preparation and impurities of Oxaliplatin were summarized based on the recent documents, which generalize the impurity organization, impurity controlling and preparation stability. The principal impurities in Oxaliplatin ...
The research progress on the preparation and impurities of Oxaliplatin were summarized based on the recent documents, which generalize the impurity organization, impurity controlling and preparation stability. The principal impurities in Oxaliplatin ...
2012, 30(6): 415-417,474.
doi: 10.3969/j.issn.1006-0111.2012.06.005
Abstract:
The definition, evaluation methods, grade classification, research status, influence factors and intervention measures of the compliance in the treatment of depression were reviewed in this paper based on the literatures home and aboard. It was clari...
The definition, evaluation methods, grade classification, research status, influence factors and intervention measures of the compliance in the treatment of depression were reviewed in this paper based on the literatures home and aboard. It was clari...
2012, 30(6): 418-421.
doi: 10.3969/j.issn.1006-0111.2012.06.006
Abstract:
Generally azole antifungal drugs possessed chiral center. After administration of the racemate, the results indicated the differences in plasma concentrations and pharmacokinetic parameters between enantiomers were stereoselctive. The metabolism migh...
Generally azole antifungal drugs possessed chiral center. After administration of the racemate, the results indicated the differences in plasma concentrations and pharmacokinetic parameters between enantiomers were stereoselctive. The metabolism migh...
2012, 30(6): 422-426,461.
doi: 10.3969/j.issn.1006-0111.2012.06.007
Abstract:
Objective To design, synthesize and study the anti-tumor activity in vitro of N-Phenyl-2-(4-phenyl)-cyclopropane-1-carboxylic acid-1-amide compounds. Methods The target compounds were obtained through knoevenagel condensation, cyclization, hydroly...
Objective To design, synthesize and study the anti-tumor activity in vitro of N-Phenyl-2-(4-phenyl)-cyclopropane-1-carboxylic acid-1-amide compounds. Methods The target compounds were obtained through knoevenagel condensation, cyclization, hydroly...
2012, 30(6): 427-429.
doi: 10.3969/j.issn.1006-0111.2012.06.008
Abstract:
Objective To design and synthesize genistein's derivatives:5-hydroxy-4'-nitro-7 -substituted benzyloxo-isoflavones and evaluate the antitumor effects in vitro. Methods Benzyl chloride was used as the starting reagent, to obtain title compounds by ...
Objective To design and synthesize genistein's derivatives:5-hydroxy-4'-nitro-7 -substituted benzyloxo-isoflavones and evaluate the antitumor effects in vitro. Methods Benzyl chloride was used as the starting reagent, to obtain title compounds by ...
2012, 30(6): 430-432,456.
doi: 10.3969/j.issn.1006-0111.2012.06.009
Abstract:
Objective To study the biological activity of 1H-pyrrol-2(5H)-ones which introduced substituted phenyl group as side chain. Methods By introduction of 5-substituted phenyl group, a serial 1H-pyrrol-2(5H)-ones were synthesized and their structures ...
Objective To study the biological activity of 1H-pyrrol-2(5H)-ones which introduced substituted phenyl group as side chain. Methods By introduction of 5-substituted phenyl group, a serial 1H-pyrrol-2(5H)-ones were synthesized and their structures ...
2012, 30(6): 433-436.
doi: 10.3969/j.issn.1006-0111.2012.06.010
Abstract:
Objective To develop a new high performance liquid chromatography (HPLC) coupled with Evaporative Light Scattering Detector (ELSD) method for simultaneous determination of four major steroid glycosides (Timosaponin B, Timosaponin E1, Timosaponin BⅡ ...
Objective To develop a new high performance liquid chromatography (HPLC) coupled with Evaporative Light Scattering Detector (ELSD) method for simultaneous determination of four major steroid glycosides (Timosaponin B, Timosaponin E1, Timosaponin BⅡ ...
2012, 30(6): 437-439,472.
doi: 10.3969/j.issn.1006-0111.2012.06.011
Abstract:
Objective To analyze chemical constituents of Scutellaria barbata D.Don by high pressure liquid chromatography-time of flight mass spectrometry (HPLC-TOF/MS). Methods A SHISEIDO CAPCELL PAK C18 (100 mm×3.0 mm, 3 μm) was used to separate. The mobil...
Objective To analyze chemical constituents of Scutellaria barbata D.Don by high pressure liquid chromatography-time of flight mass spectrometry (HPLC-TOF/MS). Methods A SHISEIDO CAPCELL PAK C18 (100 mm×3.0 mm, 3 μm) was used to separate. The mobil...
2012, 30(6): 440-442,466.
doi: 10.3969/j.issn.1006-0111.2012.06.012
Abstract:
Objective To study the penetration enhancement of electret and united Azone on cyclosporin A transdermalde livery in vitro. Methods Using corona charged -500 V, -1 000 V and -2 000 V polypropylene (PP) as electrets, 1%, 3% and 5% Azone as chemical...
Objective To study the penetration enhancement of electret and united Azone on cyclosporin A transdermalde livery in vitro. Methods Using corona charged -500 V, -1 000 V and -2 000 V polypropylene (PP) as electrets, 1%, 3% and 5% Azone as chemical...
2012, 30(6): 443-446.
doi: 10.3969/j.issn.1006-0111.2012.06.013
Abstract:
Objective To investigate the therapeutic effects of Thesium chinensis Turcz on Adriamycin-induced nephropathy rats. Methods 40 SD rats were divided into 4 groups averagely:normal control group, model control group, low-dosage group (1.0 g/(kg·d) a...
Objective To investigate the therapeutic effects of Thesium chinensis Turcz on Adriamycin-induced nephropathy rats. Methods 40 SD rats were divided into 4 groups averagely:normal control group, model control group, low-dosage group (1.0 g/(kg·d) a...
2012, 30(6): 447-448.
doi: 10.3969/j.issn.1006-0111.2012.06.014
Abstract:
Objective To observe the efficiency and safety of thalidomide combined with dexamethasone in elderly patients with multiple myeloma. Methods A total of 50 elderly patients with multiple myeloma in initial treatment were administered thalidomide co...
Objective To observe the efficiency and safety of thalidomide combined with dexamethasone in elderly patients with multiple myeloma. Methods A total of 50 elderly patients with multiple myeloma in initial treatment were administered thalidomide co...
2012, 30(6): 449-450.
doi: 10.3969/j.issn.1006-0111.2012.06.015
Abstract:
Objective To explore the effect of dermlin combined nursing care in treatment of superficial degree Ⅱ burn. Methods By simple randomization, the patients were assigned to the control group and the observed group(accepted the treatment of dermlin). ...
Objective To explore the effect of dermlin combined nursing care in treatment of superficial degree Ⅱ burn. Methods By simple randomization, the patients were assigned to the control group and the observed group(accepted the treatment of dermlin). ...
2012, 30(6): 451-453.
doi: 10.3969/j.issn.1006-0111.2012.06.016
Abstract:
Objective To establish the determination method of Quercetin content in Gnaphalium affine D. Don. Methods VP-ODS Cl8(4.6 mm×150 mm, 5 μm) colmnn was used, the mobile phase was methanol-0.2% phosphoric acid solution(45:55) with the flow rate as 1.0...
Objective To establish the determination method of Quercetin content in Gnaphalium affine D. Don. Methods VP-ODS Cl8(4.6 mm×150 mm, 5 μm) colmnn was used, the mobile phase was methanol-0.2% phosphoric acid solution(45:55) with the flow rate as 1.0...
2012, 30(6): 454-456.
doi: 10.3969/j.issn.1006-0111.2012.06.017
Abstract:
Objective To develop a method of headspace capillary gas chromatography for determining residual organic solvents in loperamide hydrochloride. Methods The carrier gas was nitrogen and FID as detector. The nine organic solvents including methanol, ...
Objective To develop a method of headspace capillary gas chromatography for determining residual organic solvents in loperamide hydrochloride. Methods The carrier gas was nitrogen and FID as detector. The nine organic solvents including methanol, ...
2012, 30(6): 457-458,477.
doi: 10.3969/j.issn.1006-0111.2012.06.018
Abstract:
Objective To establish a HPLC method for determination of chlorogenic acid in the hawthorn. Methods Sunfire C18 (4.6 mm×250 mm, 5 μm) column was used. The mobile phase was methanol:sodium dihydrogen phosphate(25:75). The flow rate was 1.0 ml/min, ...
Objective To establish a HPLC method for determination of chlorogenic acid in the hawthorn. Methods Sunfire C18 (4.6 mm×250 mm, 5 μm) column was used. The mobile phase was methanol:sodium dihydrogen phosphate(25:75). The flow rate was 1.0 ml/min, ...
2012, 30(6): 459-461.
doi: 10.3969/j.issn.1006-0111.2012.06.019
Abstract:
Objective To study the quality state of pharmaceutical Tween 80 in China. Methods Pharmaceutical Tween 80 from 10 factories were sampled and examined. The irregular qualify and sensitization in TCM injection of Tween were discussed. Results Some ...
Objective To study the quality state of pharmaceutical Tween 80 in China. Methods Pharmaceutical Tween 80 from 10 factories were sampled and examined. The irregular qualify and sensitization in TCM injection of Tween were discussed. Results Some ...
2012, 30(6): 462-463,480.
doi: 10.3969/j.issn.1006-0111.2012.06.020
Abstract:
Objective To compare and evaluate the effectiveness and cost utility of vinorelbine versus gemcitabine combined with cisplatin of advanced non-small cell lung cancer. Methods 60 advanced patients wit NSCLC were enrolled into two groups, the effect...
Objective To compare and evaluate the effectiveness and cost utility of vinorelbine versus gemcitabine combined with cisplatin of advanced non-small cell lung cancer. Methods 60 advanced patients wit NSCLC were enrolled into two groups, the effect...
2012, 30(6): 464-466.
doi: 10.3969/j.issn.1006-0111.2012.06.021
Abstract:
Objective To describe the work pattern for rationality checking of the orders in Pharmacy intravenous admixture center. Methods Irrational orders checked from Jan. to Oct. in 2011 were analyzed to evaluate the rationality and practicability of the...
Objective To describe the work pattern for rationality checking of the orders in Pharmacy intravenous admixture center. Methods Irrational orders checked from Jan. to Oct. in 2011 were analyzed to evaluate the rationality and practicability of the...
2012, 30(6): 467-469,474.
doi: 10.3969/j.issn.1006-0111.2012.06.022
Abstract:
Objective To study the rational use of antibiotic injections for pediatric in outpatient department in our hospital. Methods 669 prescriptions of pediatric outpatient from January to August of 2011 were randomly collected, according to the Antibiot...
Objective To study the rational use of antibiotic injections for pediatric in outpatient department in our hospital. Methods 669 prescriptions of pediatric outpatient from January to August of 2011 were randomly collected, according to the Antibiot...
2012, 30(6): 470-472.
doi: 10.3969/j.issn.1006-0111.2012.06.023
Abstract:
Objective To discuss the factors of epileptic seizure caused by metronidazole injection and give some prevention measure. Methods A case of epileptic seizure caused by metronidazole injection were analyzed, and the literatures about epileptic seizu...
Objective To discuss the factors of epileptic seizure caused by metronidazole injection and give some prevention measure. Methods A case of epileptic seizure caused by metronidazole injection were analyzed, and the literatures about epileptic seizu...
2012, 30(6): 475-477.
doi: 10.3969/j.issn.1006-0111.2012.06.025
Abstract:
According to the situation of pharmacy administration in our school, certain beneficial improvement method and assumption on Pharmacy Administration Course were put forward, in related to the teaching method, content as well as resource of teacher ac...
According to the situation of pharmacy administration in our school, certain beneficial improvement method and assumption on Pharmacy Administration Course were put forward, in related to the teaching method, content as well as resource of teacher ac...
2012, 30(6): 478-480.
doi: 10.3969/j.issn.1006-0111.2012.06.026
Abstract:
Objective To summarize the practice of pharmacy continuing education in recent years and gather experiences for improving teaching quality and teaching standard of the continuing education. Methods Adult learners' characteristic was analyzed and c...
Objective To summarize the practice of pharmacy continuing education in recent years and gather experiences for improving teaching quality and teaching standard of the continuing education. Methods Adult learners' characteristic was analyzed and c...
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