Keywords: 
• antibiotics /
• hospital-acquired infection,rational drug use, resistance to antibiotics /
•  /

Abstract: 158 discharged in-patient records from Jan to Jun.1997 were randomly sampled, of which 122 cases used antibiotics were studied.There were 68 patients (55.7%) used antibiotics inappropriately; 81 cases used it for prevention, 35 cases for treatment, 6 cases for both.7 cases developed hospital-acquired infection.42 cases used only 1 antibiotics, 32 cases used 2 antibiotics,48 cases used more than 2 antibiotics,the top were 7 antibiotics.122 patients involved in 196 therapeutic courses (TC) and 2007 days of 45 kinds antibiotics used totally, 111 TC used only 1 antibiotics, 59 TC used 2 antibiotics at the same time, 26 cases used more than 2 antibiotics simultaneously, the top were 6 antibiotics' combination, the average days per TC and per case for antibiotics use were 10.2 and 16.5 respectively.we discussed the relationship between antibiotics abuse and hospital-acquired infection, and the problems involved in antibiotics use for prevention, and provided a few suggestions for rational use of antibiotics.