摘要:
随机抽取我院 97年1~6月份出院病历 158份,其中 122份(77.2%)使用了抗菌药,本文仅对此122份使用抗菌药情况进行综合分析.我们发现:有68例病人(55.7%)抗菌药使用不合理;有81例为预防性使用抗菌药,治疗用药仅35例,防治兼顾有6例;有7例发生医院感染;住院期间只使用过1种抗菌药的有42例,用过2种有32例,2种以上有48例,最多为7种;共用抗菌药45种,196疗程,其中1联111疗程,2联59疗程,3联20疗程,3联以上6疗程,最多1例为6联,共计用药2007d,平均每疗程10.2d,每例平均用药16.5d.本文还讨论了抗菌药滥用与院内感染的关系,以及目前预防用药存在的问题,并对如何合理使用抗菌药提出了几点建议.
关键词:
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抗菌药 /
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医院感染 /
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合理用药 /
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耐药性
Abstract:
158 discharged in-patient records from Jan to Jun.1997 were randomly sampled, of which 122 cases used antibiotics were studied.There were 68 patients (55.7%) used antibiotics inappropriately; 81 cases used it for prevention, 35 cases for treatment, 6 cases for both.7 cases developed hospital-acquired infection.42 cases used only 1 antibiotics, 32 cases used 2 antibiotics,48 cases used more than 2 antibiotics,the top were 7 antibiotics.122 patients involved in 196 therapeutic courses (TC) and 2007 days of 45 kinds antibiotics used totally, 111 TC used only 1 antibiotics, 59 TC used 2 antibiotics at the same time, 26 cases used more than 2 antibiotics simultaneously, the top were 6 antibiotics' combination, the average days per TC and per case for antibiotics use were 10.2 and 16.5 respectively.we discussed the relationship between antibiotics abuse and hospital-acquired infection, and the problems involved in antibiotics use for prevention, and provided a few suggestions for rational use of antibiotics.