2016 Vol. 34, No. 5
Display Method:
2016, 34(5): 385-388,402.
doi: 10.3969/j.issn.1006-0111.2016.05.001
Abstract:
Human cytochrome P450 (CYP) 3A, which is widely involved in the various drug metabolism, is most abundant in liver and intestine. The activity of CYP3A enzyme may be induced or inhibited in the process of drug metabolisms, and affect the metabolism o...
Human cytochrome P450 (CYP) 3A, which is widely involved in the various drug metabolism, is most abundant in liver and intestine. The activity of CYP3A enzyme may be induced or inhibited in the process of drug metabolisms, and affect the metabolism o...
2016, 34(5): 389-392,398.
doi: 10.3969/j.issn.1006-0111.2016.05.002
Abstract:
Clopidogrel is commonly used as an anti-platelet aggregation drug in the clinical treatment, which is often used in combination with traditional Chinese medicine. Strengthening the study on the interaction mechanism of Chinese herbal medicine and its...
Clopidogrel is commonly used as an anti-platelet aggregation drug in the clinical treatment, which is often used in combination with traditional Chinese medicine. Strengthening the study on the interaction mechanism of Chinese herbal medicine and its...
2016, 34(5): 393-395,473.
doi: 10.3969/j.issn.1006-0111.2016.05.003
Abstract:
Seaweed polysaccharides are not only a direct inhibitory effect on tumor cells, but also an indirect therapeutic effected by enhancing immune function or inhibiting tumor cell metastasis. Seaweed polysaccharides could inhibit the growth of tumor cell...
Seaweed polysaccharides are not only a direct inhibitory effect on tumor cells, but also an indirect therapeutic effected by enhancing immune function or inhibiting tumor cell metastasis. Seaweed polysaccharides could inhibit the growth of tumor cell...
2016, 34(5): 396-398.
doi: 10.3969/j.issn.1006-0111.2016.05.004
Abstract:
Chinese medicinal materials, as main treatment measures, are commonly used in clinic practice of Chinese traditional medicine with long history, and a significant proportion of Chinese medicinal material resources are from wild resource. Unreasonable...
Chinese medicinal materials, as main treatment measures, are commonly used in clinic practice of Chinese traditional medicine with long history, and a significant proportion of Chinese medicinal material resources are from wild resource. Unreasonable...
2016, 34(5): 399-402.
doi: 10.3969/j.issn.1006-0111.2016.05.005
Abstract:
Objective To investigate the effect against exercise-indused fatigue in mice by aqueous extract of Ludisia discolor and its mechanism. Methods Male mice were randomly divided into five groups including low, middle, high dose groups [aqueous extrac...
Objective To investigate the effect against exercise-indused fatigue in mice by aqueous extract of Ludisia discolor and its mechanism. Methods Male mice were randomly divided into five groups including low, middle, high dose groups [aqueous extrac...
2016, 34(5): 403-407,415.
doi: 10.3969/j.issn.1006-0111.2016.05.006
Abstract:
Objective Experimental study on effects of Yangxinshi tablets in the prevention and treatment of chronic ischemic heart failure and acute myocardial ischemia reperfusion injury in order to provide a theoretical basis for its clinical application. M...
Objective Experimental study on effects of Yangxinshi tablets in the prevention and treatment of chronic ischemic heart failure and acute myocardial ischemia reperfusion injury in order to provide a theoretical basis for its clinical application. M...
2016, 34(5): 408-411.
doi: 10.3969/j.issn.1006-0111.2016.05.007
Abstract:
Objective To discuss the signficance using nutrtional risk screening (NRS) to evaluate nutritional status in patients with severe stroke. In the meantime compare the clinical application value between enteral and parenteral nutritional support thera...
Objective To discuss the signficance using nutrtional risk screening (NRS) to evaluate nutritional status in patients with severe stroke. In the meantime compare the clinical application value between enteral and parenteral nutritional support thera...
2016, 34(5): 412-415.
doi: 10.3969/j.issn.1006-0111.2016.05.008
Abstract:
Objective To evaluate effects of dexmedetomidine on onset, duration of supraclavicular brachial plexus block induced by levobupivacaine and postoperative analgesia with ultrasound guide. Methods Eighty patients undergoing elective surgeries of dis...
Objective To evaluate effects of dexmedetomidine on onset, duration of supraclavicular brachial plexus block induced by levobupivacaine and postoperative analgesia with ultrasound guide. Methods Eighty patients undergoing elective surgeries of dis...
2016, 34(5): 416-420,449.
doi: 10.3969/j.issn.1006-0111.2016.05.009
Abstract:
Objective To obtain iridoid glycosides with relatively high purity by the optimization of the preparation process of iridoid glycosides from Lamioplomisrotata. Methods Used methanol-water mobile phase with gradient run to set up an HPLC method and...
Objective To obtain iridoid glycosides with relatively high purity by the optimization of the preparation process of iridoid glycosides from Lamioplomisrotata. Methods Used methanol-water mobile phase with gradient run to set up an HPLC method and...
2016, 34(5): 421-423,446.
doi: 10.3969/j.issn.1006-0111.2016.05.010
Abstract:
Objective To clarify the necessity of therapeutic drug monitoring (TDM) of voriconazole, and give relevant clinical tips, by comparing the plasma concentration of different clinical specialties before and after adjustment of dose. Methods This is ...
Objective To clarify the necessity of therapeutic drug monitoring (TDM) of voriconazole, and give relevant clinical tips, by comparing the plasma concentration of different clinical specialties before and after adjustment of dose. Methods This is ...
2016, 34(5): 424-427.
doi: 10.3969/j.issn.1006-0111.2016.05.011
Abstract:
Objective To establish the quality control standards for Compound caulis Polygoni multiflori mixture. Methods Caulis polygoni multiflori, cortex alibiziae and schisand chinensis were identified by TLC, total flavonoids were determined by UV. Resu...
Objective To establish the quality control standards for Compound caulis Polygoni multiflori mixture. Methods Caulis polygoni multiflori, cortex alibiziae and schisand chinensis were identified by TLC, total flavonoids were determined by UV. Resu...
2016, 34(5): 428-430,440.
doi: 10.3969/j.issn.1006-0111.2016.05.012
Abstract:
Objective To develop a HPLC-fluorescence method to determine levofloxacin concentration in plasma for studying bioequivalence of levofloxacin hydrochloride tablet in Chinese healthy volunteers. Methods A single-dose of 0.2 g test or reference prep...
Objective To develop a HPLC-fluorescence method to determine levofloxacin concentration in plasma for studying bioequivalence of levofloxacin hydrochloride tablet in Chinese healthy volunteers. Methods A single-dose of 0.2 g test or reference prep...
2016, 34(5): 431-436,454.
doi: 10.3969/j.issn.1006-0111.2016.05.013
Abstract:
Objective To study the chemical constituents from the Stichopus variegatus. Method The compounds were isolated and purified by silica gel column chromatography, Sephadex LH-20 gel filtration and recrystallization. The structures of these compounds...
Objective To study the chemical constituents from the Stichopus variegatus. Method The compounds were isolated and purified by silica gel column chromatography, Sephadex LH-20 gel filtration and recrystallization. The structures of these compounds...
2016, 34(5): 437-440.
doi: 10.3969/j.issn.1006-0111.2016.05.014
Abstract:
Objective To analyze the outputof hotliteratures on pharmacology & toxicology in the world. Methods Essential Science Indicators Database were retrievedandthe national distribution, published journals and hot research topics of hot literatures wer...
Objective To analyze the outputof hotliteratures on pharmacology & toxicology in the world. Methods Essential Science Indicators Database were retrievedandthe national distribution, published journals and hot research topics of hot literatures wer...
2016, 34(5): 441-442.
doi: 10.3969/j.issn.1006-0111.2016.05.015
Abstract:
Objective To develop a HPLC method for psoralenand angelicin content assay in Zhuanggu granules. Methods Agilent Zorbax C18 column(4.6 mm×250 mm, 5 μm) was used with methanol and water(45:55) as mobile phase. The detection wavelength was set at 24...
Objective To develop a HPLC method for psoralenand angelicin content assay in Zhuanggu granules. Methods Agilent Zorbax C18 column(4.6 mm×250 mm, 5 μm) was used with methanol and water(45:55) as mobile phase. The detection wavelength was set at 24...
2016, 34(5): 443-446.
doi: 10.3969/j.issn.1006-0111.2016.05.016
Abstract:
Objective To establish a high performance liquid chromatography method for the determination of matrine in Lefu oral liquid. Methods The HPLC method was performed on a Diamonsil Platisil NH2 column (4.6 mm×250 mm, 5 μm) with the mobile phase of ac...
Objective To establish a high performance liquid chromatography method for the determination of matrine in Lefu oral liquid. Methods The HPLC method was performed on a Diamonsil Platisil NH2 column (4.6 mm×250 mm, 5 μm) with the mobile phase of ac...
2016, 34(5): 447-449.
doi: 10.3969/j.issn.1006-0111.2016.05.017
Abstract:
Objective To establish an HPLC quantitative method for the content determination of baicalin in Kangdeling capsule. Methods The chromatography column was Agilent Tc-C18-WR (4.6 mm×250 mm,5 μm),and the column temperature was 30 ℃.The mobile phase c...
Objective To establish an HPLC quantitative method for the content determination of baicalin in Kangdeling capsule. Methods The chromatography column was Agilent Tc-C18-WR (4.6 mm×250 mm,5 μm),and the column temperature was 30 ℃.The mobile phase c...
2016, 34(5): 450-454.
doi: 10.3969/j.issn.1006-0111.2016.05.018
Abstract:
Objective To establish a quality control standard for Qingre Baidu granules. Methods Isatidis Radix, Fructus Forsythiae,Herba Violae, and Glycyrrhizae were identified by TLC, and the concentration of chlorogenic acid was determined by HPLC. This m...
Objective To establish a quality control standard for Qingre Baidu granules. Methods Isatidis Radix, Fructus Forsythiae,Herba Violae, and Glycyrrhizae were identified by TLC, and the concentration of chlorogenic acid was determined by HPLC. This m...
2016, 34(5): 455-458.
doi: 10.3969/j.issn.1006-0111.2016.05.019
Abstract:
Objective To optimize the cream base of benzhydramine hydroehloride. Methods Five nonionic surfactants as an emulsifier were used to prepare benzhydramine hydroehloride creams. The five sorts of cream were evaluated from the appearance,preliminary...
Objective To optimize the cream base of benzhydramine hydroehloride. Methods Five nonionic surfactants as an emulsifier were used to prepare benzhydramine hydroehloride creams. The five sorts of cream were evaluated from the appearance,preliminary...
2016, 34(5): 459-462.
doi: 10.3969/j.issn.1006-0111.2016.05.020
Abstract:
Objective To summarize the clinical experience of bortezomib-based treatment for Waldenström macroglobulinemia and evaluate the therapeutic efficacy and safety. Methods The clinical data were collected for 15 patients with Waldenström macroglobuli...
Objective To summarize the clinical experience of bortezomib-based treatment for Waldenström macroglobulinemia and evaluate the therapeutic efficacy and safety. Methods The clinical data were collected for 15 patients with Waldenström macroglobuli...
2016, 34(5): 463-465.
doi: 10.3969/j.issn.1006-0111.2016.05.021
Abstract:
Objective To evaluate the suppressive effect of dezocine, lidocaine and ephedrine on fentanyl-induced cough. Methods A total of 120 patients ASA I-II, scheduled for elective surgery under general anesthesia, were randomly allocated into four group...
Objective To evaluate the suppressive effect of dezocine, lidocaine and ephedrine on fentanyl-induced cough. Methods A total of 120 patients ASA I-II, scheduled for elective surgery under general anesthesia, were randomly allocated into four group...
2016, 34(5): 466-468,477.
doi: 10.3969/j.issn.1006-0111.2016.05.022
Abstract:
Objective To evaluate opioids utilization of cancer ached inpatients in the integrative traditional Chinese and western medicine hospital and provide suggestion for the rational utilization of opioids. Method DDDs,DUI,the distribution of cancer pa...
Objective To evaluate opioids utilization of cancer ached inpatients in the integrative traditional Chinese and western medicine hospital and provide suggestion for the rational utilization of opioids. Method DDDs,DUI,the distribution of cancer pa...
2016, 34(5): 469-473.
doi: 10.3969/j.issn.1006-0111.2016.05.023
Abstract:
Objective To formulate the clinical application specification of antibiotics, make a deference index of antibacterial drugs in chest department according to the investigation about the antibiotics' utility situation in chest department in 2014 and p...
Objective To formulate the clinical application specification of antibiotics, make a deference index of antibacterial drugs in chest department according to the investigation about the antibiotics' utility situation in chest department in 2014 and p...
2016, 34(5): 474-477.
doi: 10.3969/j.issn.1006-0111.2016.05.024
Abstract:
Objective To investigate the effect of clinical pharmacists in the analgesic therapysoas to improve the rational use of analgesic drugs. Methods Clinical pharmacists participated in the formulation of drug therapy plan for the patient of cancer pa...
Objective To investigate the effect of clinical pharmacists in the analgesic therapysoas to improve the rational use of analgesic drugs. Methods Clinical pharmacists participated in the formulation of drug therapy plan for the patient of cancer pa...
2016, 34(5): 478-480.
doi: 10.3969/j.issn.1006-0111.2016.05.025
Abstract:
Objective To enhance oral tablets ward pharmacy inventory efficiency and improve the comprehensive quality of the pharmacist by QCC activities. Method Main factors to extend the ward pharmacy tablet counting time were analyzed through collecting t...
Objective To enhance oral tablets ward pharmacy inventory efficiency and improve the comprehensive quality of the pharmacist by QCC activities. Method Main factors to extend the ward pharmacy tablet counting time were analyzed through collecting t...
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