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2022 Vol. 40, No. 1

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Research progresses on the main active components in Ningxia Sophora alopecuroides and the therapeutic activities for liver diseases
QUAN Danni, XU Yue, QU Zhuo, XU Weiheng, ZHANG Wannian, ZHUANG Chunlin
2022, 40(1): 1-5, 37. doi: 10.12206/j.issn.1006-0111.202105035
Abstract(9068) HTML (2950) PDF (1040KB)(164) Cited By (5)
Abstract:
Sophora alopecuroides, a plant of the family Leguminosae, is one of the Daodi herbs in Ningxia. The active constituents of Sophora alopecuroides are abundant and complex, including alkaloids, flavonoids, volatile oils, steroids, polysaccharides, fatt...
The research progress on the basic characteristics and metabolic regulation of α1-acid glycoprotein
XIANG Kefa, WAN Jingjing, ZHANG Huimin, SHI Xiaofei, QIN Zhen, LIU Xia
2022, 40(1): 6-11. doi: 10.12206/j.issn.1006-0111.202105032
Abstract(7630) HTML (3095) PDF (913KB)(98) Cited By (1)
Abstract:
Metabolic homeostasis is a basic function necessary for the survival of the organism. α1-acid glycoprotein (AGP) is an acute phase protein with a glycosylation degree of up to 45%. It has high affinity and low capacity. Although the biological role o...
Effects of liver-specific Nampt knockout on ischemic stroke
QING Shengli, WANG Shuna, WANG Dongsheng, LYU Xiaoqun, XU Tianying, MIAO Chaoyu
2022, 40(1): 12-19. doi: 10.12206/j.issn.1006-0111.202107068
Abstract(8295) HTML (1683) PDF (4478KB)(30)
Abstract:
Objective  Nicotinamide phosphoribosyltransferase (Nampt) is a new therapeutic target for ischemic stroke. The aim of this study was to investigate protective effect of liver-derived Nampt on ischemic stroke.   Methods  Liver-specific Nampt knocko...
Study of ErChen decoction on the treatment of obesity polycystic ovary syndrome and obesity infertility
CAI Mengcheng, JIN Yongsheng, YU Chaoqin, CHENG wen, YU Jin, ZHOU Ling
2022, 40(1): 20-27, 52. doi: 10.12206/j.issn.1006-0111.202105078
Abstract(5025) HTML (1252) PDF (1886KB)(17) Cited By (11)
Abstract:
Objective  To explore the potential mechanism of Erchen decoction in the treatment of obese polycystic ovary syndrome and obese infertility, in order to provide theoretical basis for “treating different diseases with same method”.   Methods  The a...
Preparation and in vitro evaluation of berberine hydrochloride nanoemulsion oral drug delivery systems
DAI Weili, JIN Ying, WANG Ting, TANG Xiaomeng, GU Qing
2022, 40(1): 28-33, 43. doi: 10.12206/j.issn.1006-0111.202107081
Abstract(6158) HTML (1408) PDF (1436KB)(54) Cited By (4)
Abstract:
Objective  To prepare berberine hydrochloride nanoemulsion, optimize its formulation composition and preparation process, and investigate its in vitro characteristics.   Methods  BBR-NE was prepared by water drop addition and pseudo-ternary phase ...
Simultaneous determination of five components in Anemarrhenae Rhizoma by HPLC-ELSD
DAI Jianying, YOU Wei, TIAN Tian, HONG Zhanying
2022, 40(1): 34-37. doi: 10.12206/j.issn.1006-0111.202109070
Abstract(3908) HTML (2359) PDF (1139KB)(29) Cited By (6)
Abstract:
Objective  To establish a method for the simultaneous determination of new mangiferin, mangiferin, artemisinin BⅡ, icariin and artemisinin A in Anemarrhenae Rhizoma by high performance liquid chromatography-evaporation light scattering detector (HPL...
Characterization and function study of circadian rhythm gene CtPRR1 in Carthamus tinctorius L.
WU Jianhui, HE Beixuan, JIA Xinlei, GUO Meili
2022, 40(1): 38-43. doi: 10.12206/j.issn.1006-0111.202102007
Abstract(7524) HTML (2203) PDF (1404KB)(46) Cited By (4)
Abstract:
Objective  To explore the effect of circadian rhythm genes on flavonoids biosynthesis in safflower and its molecular mechanism.  Methods  Based on the transcriptome and metabolomic database of safflower corolla, we screened the circadian rhythm ge...
Antifungal activity study on HDAC inhibitor Rocilinostat
ZHU Tianbao, TU Jie, SHENG Chunquan, XU Defeng, LIU Na
2022, 40(1): 44-47, 65. doi: 10.12206/j.issn.1006-0111.202103008
Abstract(8570) HTML (1968) PDF (1090KB)(39)
Abstract:
Objective  To evaluate the in vitro synergistic antifungal activity of HDAC inhibitors in combination with azole drugs against azoles-resistant Candida strains.  Methods  The checkerboard microdilution method was used to evaluate the antifungal ac...
Rapid prediction of antioxidant activity in aqueous extract solutions of melastoma dodecandrum by ultraviolet spectroscopy
JIANG Cheng, XU Pingcui, WU Renjie, ZHANG Xiaoqing, CHEN Liping, WANG Nani
2022, 40(1): 48-52. doi: 10.12206/j.issn.1006-0111.202101016
Abstract(8204) HTML (1540) PDF (1181KB)(16) Cited By (2)
Abstract:
Objective  To establish a rapid prediction method of the antioxidant activity in aqueous extract solutions of Melastoma dodecandrum based on ultraviolet spectroscopy and partial least squares regression algorithm.   Methods  The DPPH free radical ...
The total synthesis of natural cyclopeptide auyuittuqamide A
GENG Chenchen, WANG Tiantian, LI Xiang, Wang Xiaoyan, JIANG Yunyun
2022, 40(1): 53-56, 61. doi: 10.12206/j.issn.1006-0111.202105087
Abstract(8350) HTML (1996) PDF (1184KB)(84)
Abstract:
Objective  To synthesize the natural cyclopeptide auyuittuqamide A by Fmoc-based solid phase linear synthesis and liquid phase cyclization.   Methods  Using 2-chlorotriphenylmethyl chloride (CTC) resin as the solid support, 1,3-diisopropylcarbodii...
Study on quality standard for vinegar-steamed Corydalis rhizoma
LIN Yuan, WEI Yuchen, LI Xiaodong, BU Qitao, XU Shihui, ZHANG Chengzhong
2022, 40(1): 57-61. doi: 10.12206/j.issn.1006-0111.202102015
Abstract(4842) HTML (1851) PDF (1131KB)(22) Cited By (3)
Abstract:
Objective  To set up the quality standards for vinegar-steamed Corydalis rhizome, which can be used for the quality control of production, supervision, circulation and application of the steam processed Corydalis rhizoma with vinegar.   Methods  T...
Determination of zolpidem tartrate tablets after radiation by UHPLC
ZHANG Wen, HUANG Xinhui, YANG Xingrui, ZHOU Tingting, GAO Jianyi, LI Yongzhi
2022, 40(1): 62-65. doi: 10.12206/j.issn.1006-0111.202110019
Abstract(3812) HTML (1103) PDF (1006KB)(12)
Abstract:
Objective  To establish a UHPLC method for the determination of zolpidem tartrate tablets after radiation, and to investigate the effect of different radiation doses on the content of zolpidem tartrate tablets.   Methods  Ultra high performance li...
In vitro release study on self-microemulsion of curcumin and piperine
REN Jinmei, LI Man, WANG Jing, GU Shenyong
2022, 40(1): 66-69, 75. doi: 10.12206/j.issn.1006-0111.202009090
Abstract(8902) HTML (2150) PDF (1050KB)(74) Cited By (3)
Abstract:
Objective  To study the release profile of curcumin and piperine from the compound self-microemulsion.  Methods  The release of curcumin and piperine in vitro was investigated by dynamic dialysis under the condition of phosphate buffer of pH 4.8 a...
Comparative study on analgesic effect of tetrodotoxin in four acute pain models
CHEN Xuejun, ZHANG Ruihua, SHI Tong, WANG Chen, XU Jianfu, LI Liqin
2022, 40(1): 70-75. doi: 10.12206/j.issn.1006-0111.202101009
Abstract(10171) HTML (2412) PDF (1468KB)(71) Cited By (3)
Abstract:
Objective  To evaluate the analgesic effect of tetrodotoxin (TTX) in four types of acute pain models and provide experimental support for its rational application.  Methods  Mice or rats were intramuscularly pretreated with morphine (1 mg/kg) or T...
Study on quality standard of compound Yuhong suppository
HU Yeshuai, TANG Xiaomeng, WANG Zhijun, HUANG Yueying, WANG Xiaojun, SONG Hongjie
2022, 40(1): 76-78, 83. doi: 10.12206/j.issn.1006-0111.202103003
Abstract(7106) HTML (1533) PDF (1109KB)(23)
Abstract:
Objective  To establish the quality standard of compound Yuhong suppository.   Methods  Angelica dahurica, colophony and Sophora flavescens Alt. were identified by thin layer chromatography(TLC)method. The contents of sulfadiazine and dyclonine hy...
The effects of Shexiang Baoxin pills combined with intracoronary injection of nicorandil on myocardial blood perfusion and short-term prognosis for STEMI patients after PPCI
HUANG Jingjing, CHEN Hao, LI Linrui, LUO Zhurong, LIN Xianliang
2022, 40(1): 79-83. doi: 10.12206/j.issn.1006-0111.202008009
Abstract(4676) HTML (1660) PDF (999KB)(22) Cited By (8)
Abstract:
Objective  To observe the effects of Shexiang Baoxin pill combined with intracoronary injection of nicorandil on myocardial perfusion and short-term prognosis after primary percutaneous coronary intervention in patients with ST-segment elevation myo...
Clinical features and treatment of calcineurin inhibitor-induced pain syndrome in renal transplant recipients
TONG Ling, FAN Xing, YU Airong
2022, 40(1): 84-88. doi: 10.12206/j.issn.1006-0111.202101014
Abstract(6396) HTML (2020) PDF (927KB)(56) Cited By (3)
Abstract:
Objective  To understand the clinical features and therapeutic methods for calcineurin inhibitor-induced pain syndrome (CIPS) in kidney transplant recipients.  Methods  The related articles or abstracts from January 1991 to December 2020 were obta...
Effects of antihypertensive drugs on renal function after percutaneous transluminal coronary angioplasty
JIANG Huiyan, YAN Simin, GE Weihong
2022, 40(1): 89-92. doi: 10.12206/j.issn.1006-0111.202101020
Abstract(4405) HTML (1418) PDF (847KB)(23) Cited By (1)
Abstract:
Objective  To evaluate the effects of antihypertensive drugs on renal function after percutaneous transluminal coronary angioplasty.  Methods  A retrospective analysis was performed on 193 patients who underwent percutaneous transluminal coronary ...
Analysis on 59 cases of preparation deviation in our hospital from 2017 to 2019
LI Jie, YANG Yuru, YANG Bashi, WANG Qingfen, CHEN Jinshan
2022, 40(1): 93-96. doi: 10.12206/j.issn.1006-0111.202008006
Abstract(8931) HTML (2470) PDF (1020KB)(312) Cited By (1)
Abstract:
Objective  To provide direction for the improvement of quality control of hospital preparations and ensure the safety for clinical use by analyzing the hospital preparation deviations in recent three years.  Methods  A retrospective analysis on 59...