2022 Vol. 40, No. 1
Display Method:
2022, 40(1): 1-5, 37.
doi: 10.12206/j.issn.1006-0111.202105035
Abstract:
Sophora alopecuroides, a plant of the family Leguminosae, is one of the Daodi herbs in Ningxia. The active constituents of Sophora alopecuroides are abundant and complex, including alkaloids, flavonoids, volatile oils, steroids, polysaccharides, fatt...
Sophora alopecuroides, a plant of the family Leguminosae, is one of the Daodi herbs in Ningxia. The active constituents of Sophora alopecuroides are abundant and complex, including alkaloids, flavonoids, volatile oils, steroids, polysaccharides, fatt...
2022, 40(1): 6-11.
doi: 10.12206/j.issn.1006-0111.202105032
Abstract:
Metabolic homeostasis is a basic function necessary for the survival of the organism. α1-acid glycoprotein (AGP) is an acute phase protein with a glycosylation degree of up to 45%. It has high affinity and low capacity. Although the biological role o...
Metabolic homeostasis is a basic function necessary for the survival of the organism. α1-acid glycoprotein (AGP) is an acute phase protein with a glycosylation degree of up to 45%. It has high affinity and low capacity. Although the biological role o...
2022, 40(1): 12-19.
doi: 10.12206/j.issn.1006-0111.202107068
Abstract:
Objective Nicotinamide phosphoribosyltransferase (Nampt) is a new therapeutic target for ischemic stroke. The aim of this study was to investigate protective effect of liver-derived Nampt on ischemic stroke. Methods Liver-specific Nampt knocko...
2022, 40(1): 20-27, 52.
doi: 10.12206/j.issn.1006-0111.202105078
Abstract:
Objective To explore the potential mechanism of Erchen decoction in the treatment of obese polycystic ovary syndrome and obese infertility, in order to provide theoretical basis for “treating different diseases with same method”. Methods The a...
2022, 40(1): 28-33, 43.
doi: 10.12206/j.issn.1006-0111.202107081
Abstract:
Objective To prepare berberine hydrochloride nanoemulsion, optimize its formulation composition and preparation process, and investigate its in vitro characteristics. Methods BBR-NE was prepared by water drop addition and pseudo-ternary phase ...
2022, 40(1): 34-37.
doi: 10.12206/j.issn.1006-0111.202109070
Abstract:
Objective To establish a method for the simultaneous determination of new mangiferin, mangiferin, artemisinin BⅡ, icariin and artemisinin A in Anemarrhenae Rhizoma by high performance liquid chromatography-evaporation light scattering detector (HPL...
2022, 40(1): 38-43.
doi: 10.12206/j.issn.1006-0111.202102007
Abstract:
Objective To explore the effect of circadian rhythm genes on flavonoids biosynthesis in safflower and its molecular mechanism. Methods Based on the transcriptome and metabolomic database of safflower corolla, we screened the circadian rhythm ge...
2022, 40(1): 44-47, 65.
doi: 10.12206/j.issn.1006-0111.202103008
Abstract:
Objective To evaluate the in vitro synergistic antifungal activity of HDAC inhibitors in combination with azole drugs against azoles-resistant Candida strains. Methods The checkerboard microdilution method was used to evaluate the antifungal ac...
2022, 40(1): 48-52.
doi: 10.12206/j.issn.1006-0111.202101016
Abstract:
Objective To establish a rapid prediction method of the antioxidant activity in aqueous extract solutions of Melastoma dodecandrum based on ultraviolet spectroscopy and partial least squares regression algorithm. Methods The DPPH free radical ...
2022, 40(1): 53-56, 61.
doi: 10.12206/j.issn.1006-0111.202105087
Abstract:
Objective To synthesize the natural cyclopeptide auyuittuqamide A by Fmoc-based solid phase linear synthesis and liquid phase cyclization. Methods Using 2-chlorotriphenylmethyl chloride (CTC) resin as the solid support, 1,3-diisopropylcarbodii...
2022, 40(1): 57-61.
doi: 10.12206/j.issn.1006-0111.202102015
Abstract:
Objective To set up the quality standards for vinegar-steamed Corydalis rhizome, which can be used for the quality control of production, supervision, circulation and application of the steam processed Corydalis rhizoma with vinegar. Methods T...
2022, 40(1): 62-65.
doi: 10.12206/j.issn.1006-0111.202110019
Abstract:
Objective To establish a UHPLC method for the determination of zolpidem tartrate tablets after radiation, and to investigate the effect of different radiation doses on the content of zolpidem tartrate tablets. Methods Ultra high performance li...
2022, 40(1): 66-69, 75.
doi: 10.12206/j.issn.1006-0111.202009090
Abstract:
Objective To study the release profile of curcumin and piperine from the compound self-microemulsion. Methods The release of curcumin and piperine in vitro was investigated by dynamic dialysis under the condition of phosphate buffer of pH 4.8 a...
2022, 40(1): 70-75.
doi: 10.12206/j.issn.1006-0111.202101009
Abstract:
Objective To evaluate the analgesic effect of tetrodotoxin (TTX) in four types of acute pain models and provide experimental support for its rational application. Methods Mice or rats were intramuscularly pretreated with morphine (1 mg/kg) or T...
2022, 40(1): 76-78, 83.
doi: 10.12206/j.issn.1006-0111.202103003
Abstract:
Objective To establish the quality standard of compound Yuhong suppository. Methods Angelica dahurica, colophony and Sophora flavescens Alt. were identified by thin layer chromatography(TLC)method. The contents of sulfadiazine and dyclonine hy...
2022, 40(1): 79-83.
doi: 10.12206/j.issn.1006-0111.202008009
Abstract:
Objective To observe the effects of Shexiang Baoxin pill combined with intracoronary injection of nicorandil on myocardial perfusion and short-term prognosis after primary percutaneous coronary intervention in patients with ST-segment elevation myo...
2022, 40(1): 84-88.
doi: 10.12206/j.issn.1006-0111.202101014
Abstract:
Objective To understand the clinical features and therapeutic methods for calcineurin inhibitor-induced pain syndrome (CIPS) in kidney transplant recipients. Methods The related articles or abstracts from January 1991 to December 2020 were obta...
2022, 40(1): 89-92.
doi: 10.12206/j.issn.1006-0111.202101020
Abstract:
Objective To evaluate the effects of antihypertensive drugs on renal function after percutaneous transluminal coronary angioplasty. Methods A retrospective analysis was performed on 193 patients who underwent percutaneous transluminal coronary ...
2022, 40(1): 93-96.
doi: 10.12206/j.issn.1006-0111.202008006
Abstract:
Objective To provide direction for the improvement of quality control of hospital preparations and ensure the safety for clinical use by analyzing the hospital preparation deviations in recent three years. Methods A retrospective analysis on 59...